When does the pre-load start?

November 10. On PS5 it starts at midnight local time; on Xbox it starts at 00:00 GMT, which is 7 PM ET on November 9. You download everything early and play as soon as it unlocks on November 19.

Checked by the GTA 6 Guide against Rockstar, Take-Two, official stores and the press. Sources for each fact are on the credits page.